By Dr. Andy Galpin
This info is courtesy of @dr.darrencandow on the recent @barbell_shrugged podcast.
Your brain accounts for ~20% of your whole body energy demands. TBI, neurological degenerative diseases, and disorders are all partially characterized by dysfunctional brain bioenergetics and/or altered creatine metabolism.
In total, ~12 studies exist on creatine supplementation & brain creatine level. Typical result is an ⬆️of brain creatine by 5-10% (though highly variable).
Some preliminary findings indicate creatine supplementation MAY benefit patients with TBI. Much more info needed.
However, data are must more robust for creatine supplementation benefiting:
1. Cognition (p < 0.001)
2. Personality behavior (p < 0.001)
3. Self-care (p < 0.029)
4. Communication (p < 0.018)
In total:
Cognitive Function: 12 studies showed ⬆️, 3 showed no effects
Sleep Deprivation: 2 studies showed ⬆️cognitive function
ALS: 3 studies, no benefit
Musc. Dystrophy: 2 studies showed ⬆️in strength, function, and bone
Huntington's: 3 showed neurological ⬆️3 showed none
Parkinson's: 1 showed ⬆️ strength and function, 1 did not
MS: 3 found no benefit
Depression: 6 found some ⬆️ (when combined with Rx meds)
Anxiety & PTSD: 2 found some ⬆️in cognitive ability
The following are all basically myths or HIGHLY exaggerated side effects:
1. Chronic water retention
2. It's a steroid
3. Kidney/Liver damage
4. Hair loss/baldness
5. Dehydration
Since I know you'll ask, most quality companies use creatine monohydrate, and it's all equally effective, so you can get from any of them.
Link Below to the one I use from @live.momentous (note: affiliate link) - I think it currently has a discount associated, so not a bad time to get it.
Dr. Andy Galpin
My goal is to enhance the human condition by providing the world with in-depth and entertaining health.